代表性论文： 1. Yang Y. L.; Gao, Y.; Sun, Y. Y.; Zhao, J.; Gou, S. H. Study on the anticancer potency of Ru(II)/Ir(III) complexes via DNA damage and poly(ADP-ribose) polymerase 1 inhibition. Journal of Medicinal Chemistry 2023, 66(19), 13731–13745. 2. Yang Y. L.; Zou X. F.; Sun Y. Y.; Chen F. H.; Zhao J.; Gou S. H. Naphthalene diimide-functionalized half-sandwich Ru(II) complexes as mitochondria-targeted anticancer and antimetastatic agents. Inorganic Chemistry 2023, 62(24), 9649–9660. 3. Yang Y. L.; Gao Y.; Zhao J.; Gou S. H. An electron-accepting half-sandwich iridium(III) complex for the treatment of hypoxic tumors via synergetic chemo- and phototherapy. Inorganic Chemistry Frontiers 2024, 11, 436–450. 4. Yang Y. L.; Guo L. H.; Tian Z. Z.; Gong Y. T.; Zheng H. M.; Zhang S. M.; Xu Z. S.; Ge X. X.; Liu Z. Novel and versatile imine-N-heterocyclic carbene half-sandwich iridium(III) complexes as lysosome-targeted anticancer agents. Inorganic Chemistry 2018, 57, 11087−11098. 5. Yang Y. L.; Guo L. H.; Tian Z. Z.; Ge X. X.; Gong Y. T.; Zheng H. M.; Shi S. P.; Liu Z. Lysosome-targeted phosphine-imine half-sandwich iridium(III) anticancer complexes: synthesis, characterization, and biological activity. Organometallics 2019, 38, 1761−1769. 6. Yang Y. L.; Guo L. H.; Ge X. X.; Tian Z. Z.; Gong Y. T.; Zheng H. M.; Du Q.; Zheng X. F.; Liu Z. Novel lysosome-targeted cyclometalated iridium(III) anticancer complexes containing imine-N-heterocyclic carbene ligands: synthesis, spectroscopic properties and biological activity. Dyes and pigments 2019, 161, 119–129. 7. Yang Y. L.; Guo L. H.; Tian Z. Z.; Liu X. C.; Gong Y. T.; Zheng H. M.; Ge X. X.; Liu Z. Imine-N-heterocyclic carbene as versatile ligands in ruthenium(II) p-cymene anticancer complexes: A structure-activity relationship study. Chemistry–An Asian Journal 2018, 13, 2923–2933. 8. Yang Y. L.; Guo L. H.; Ge X. X.; Shi S. P.; Gong Y. T.; Xu Z. S.; Zheng X. F.; Liu Z. Structure-activity relationships for highly potent half-sandwich organoiridium(III) anticancer complexes with C^N-chelated ligands. Journal of Inorganic Biochemistry 2019, 191, 1–7. 9. Tian Z. Z.‡; Yang Y. L.‡; Guo L. H.; Zhong G. S.; Li J. J.; Liu Z. Dual-functional cyclometalated iridium imine NHC complexes: highly potent anticancer and antimetastatic agents. Inorganic Chemistry Frontiers 2018, 5, 3106–3112. (共同一作) 10. Du Q.‡; Yang Y. L.‡; Guo L. H.; Tian M.; Ge X. X.; Tian Z. Z.; Zhao L. P.; Xu Z. S.; Li J. J.; Liu Z. Fluorescent half-sandwich phosphine-sulfonate iridium(III) and ruthenium(II) complexes as potential lysosome-targeted anticancer agents. Dyes and Pigments 2019, 162, 821–830. (共同一作) 专利： 1．一种可靶向溶酶体的卡宾亚胺半三明治铱配合物及其制备方法、应用。授权公告号：CN 108395457 B. 2．含有膦亚胺两齿螯合配体的铱抗癌配合物及其制备方法和应用。授权公告号：CN 109265488 B. 3．含有聚腺苷二磷酸核糖聚合酶-1抑制剂的环金属钌(II)配合物及其制备方法及其应用。2023，申请号：202310569696.9 |
